The United States passed a grim milestone today, hitting 250,000 coronavirus-related deaths, with the number expected to keep climbing steeply as infections surge nationwide.

Experts predict that the country could soon be reporting 2,000 deaths a day or more, matching or exceeding the spring peak, and that 100,000 to 200,000 more Americans could die in the coming months.

Just how bad it gets will depend on a variety of factors, including how well preventive measures are followed and when a vaccine is introduced.

“It all depends on what we do and how we address this outbreak,” said Jeffrey Shaman, a Columbia University epidemiologist who has modeled the spread of the disease. “That is going to determine how much it runs through us.”

Back in March, when the virus was still relatively new and limited mainly to a few significant pockets like New York, Dr. Anthony S. Fauci, the top infectious disease expert in the country, predicted that it might kill up to 240,000 Americans.

It has now passed that mark, with no end in sight.

RELATED: Hawaii reports 1 additional coronavirus death and 71 new infections

Since the beginning, preventive measures like wearing masks have been caught up in a political divide, and that remains the case today, as the Trump administration resists beginning a transition of power to President-elect Joe Biden and cooperating on a pandemic strategy.

New vaccines may begin to have an impact next year, experts said, and for now, developments in treating the disease as well as a younger population getting infected mean that far fewer people who are admitted to hospitals are dying. Infections are also being diagnosed earlier, which helps combat it.

The deadliest day of the pandemic in the United States was April 15, when the reported daily toll hit 2,752.

There is always a lag in deaths, compared with the rate of infection and hospitalizations, and with the latter measure now hitting records every day — 76,830 Americans were hospitalized Tuesday, according to the COVID Tracking Project — the death toll is certain to go on rising.

COVID-19 deaths have continued their bleak march with little respite throughout the year.

By March 24, a little more than a month into the pandemic, 50,000 people had died. That number doubled to 100,000 by May 27 and added another 50,000 within two months, by July 29. Two months later, on Sept. 22, the total reached 200,000.

Toward the end of the summer, the number of cases being reported daily in the United States eased, after a brief spike in July. But they have been soaring again since the beginning of November.

On Sept. 22, there had been somewhat more than 6.9 million total cases in the United States, according to a New York Times database. As of now, there have been more than 11.5 million.

The combination of the onset of winter, fatigue with preventive measures, holiday travel and gatherings as well as the patchwork of responses across all 50 states is expected to drive that number still higher.

“We have a lot of people who have not been infected with this yet,” Shaman said. “If you get complacent, the virus does not care. It is just going to come back.”

© 2020 The New York Times Company