ALBANY, N.Y. >> Gov. Andrew Cuomo again blasted fellow Democrats today over Amazon’s backing out of a deal to put one of its second headquarters in New York City, calling the internet retailer’s rejection the “greatest tragedy” he has seen since he’s been in government.

Cuomo also said during an interview on public radio station WAMC that losing the Amazon deal makes him sick to his stomach. His public comments were Cuomo’s first on the topic since his office issued a statement Feb. 14, the day Seattle-based Amazon announced it was backing out of an agreement to redevelop a site in Queens.

Democrats who control the state Senate bear much of the blame, Cuomo said, including Sen. Michael Gianaris, who represents the Long Island City neighborhood where Amazon wanted to base 25,000 jobs, with the potential to expand to 40,000 jobs over two decades.

During a half-hour interview in which he referenced other failed government projects, Cuomo called the collapse of the Amazon deal “the greatest tragedy that I have seen since I have been in government.”

Cuomo, a 61-year-old third-term governor whose public service career started in the 1980s, said the state Senate made the “misguided decision” to treat the Amazon agreement as a local political issue. As such, Democrats led by Senate Majority Leader Andrea Stewart-Cousins gave Gianaris, the chamber’s No. 2 lawmaker, too much influence over approving or rejecting a deal that would’ve put $27.5 billion in state coffers over the next 30 years, the governor said.

Gianaris and others opposed to the Amazon deal say they mainly objected to the $3 billion in state and city tax incentives the company stood to receive for reaching its job creation goals. The way the deal was brokered behind closed doors by Cuomo and New York Mayor Bill de Blasio, a Democrat, also helped to rally the opposition.

“It’s unfortunate that Governor Cuomo is once again failing to accept any responsibility for this failed deal,” Senate majority spokesman Michael Murphy said in a statement. “The Governor should spend less time with baseless attacks and attempts to divide Democrats and more time fixing his flawed economic development process so we can move forward and help business and the community thrive.”

Amazon called off its Long Island City plans on Valentine’s Day, after growing opposition to the project led to last-minute efforts by Cuomo to keep the deal on the table.

Meanwhile, de Blasio said it’s time New York officials move on from the Amazon debacle.

“Everyone was doing what they thought was right,” the mayor said on WNYC radio today.

He said that “a clear majority” of New Yorkers favored the jobs and revenue but added that “vibrant debate” is “normal in New York City.”