A man sustained critical injuries from a fire that destroyed two structures in Maili Tuesday.

Eleven units with more than 40 firefighters responded to the two-alarm fire at 87-124 St. John’s Road shortly after 11 a.m.

Honolulu Fire Department spokesman Capt. Jeffrey Roache said firefighters found a single-family home engulfed in flames when they arrived.

Police closed St. John’s Road between Farrington Highway and Manuaihue Street as crews battled the fire. HFD firefighters had the fire under control at around 11:40 a.m.

One home was a “total loss,” but the extent of the other structure’s damage is unknown as of this afternoon.

Roache said the injured man sustained burns to his hands and side of his body and was bleeding from the head. Shayne Enright, spokeswoman of the Honolulu Emergency Services Department, said the man is 45 years old and was taken in a private vehicle to Waianae Coast Comprehensive Health Center.

From there, EMS personnel took him to a trauma hospital in critical condition.

Enright also reported an injury sustained by a 31-year-old woman who was bitten by a dog she was trying to get away from the fire. The woman was treated at the scene and refused transportation to a hospital. Enright said it is unclear who owned the dog.

Flames also affected nearby power lines.

The American Red Cross responded to the scene to assist affected residents.

The cause of the fire is under investigation and a damage estimate has yet to be determined.